Fumarylacetoacetic acid

Fumarylacetoacetic acid

Names
Preferred IUPAC name (2E)-4,6-Dioxooct-2-enedioic acid
Identifiers
CAS Number	28613-33-4^Y 5698-51-1^Y
3D model (JSmol)	Interactive image
ChemSpider	4444081
MeSH	Fumarylacetoacetate
PubChem CID	5280398
UNII	FM3BV7K438^Y
CompTox Dashboard (EPA)	DTXSID20901388
InChI InChI=1S/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1+ Key: GACSIVHAIFQKTC-OWOJBTEDSA-N InChI=1/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1+ Key: GACSIVHAIFQKTC-OWOJBTEDBU
SMILES O=C(\C=C\C(=O)O)CC(=O)CC(=O)O
Properties
Chemical formula	C8H8O6
Molar mass	200.146 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is ^YN ?) Infobox references

Fumarylacetoacetic acid (fumarylacetoacetate) is an intermediate in the metabolism of tyrosine. It is formed through the conversion of maleylacetoacetate into fumarylacetoacetate by the enzyme maleylacetoacetate isomerase.^[1]

See also

• Fumarylacetoacetate hydrolase

References

1. W. E. Knox and M. LeMay-Knox (1951). "The oxidation in liver of l-tyrosine to acetoacetate through p-hydroxyphenylpyruvate and homogentisic acid". Biochem. J. 49 (5): 686–693. doi:10.1042/bj0490686. PMC 1197578. PMID 14886367.