After his doctor informs him he will die in six months, Professor Henry Todhunter (Thomas Mitchell) decides to spend his last days killing someone who contributes nothing but harm to society. When Henry learns that his friend Betty's (Geraldine Fitzgerald) husband, Michael (Jeffrey Lynn), has been painting forgeries of ancient paintings for gallery owner Ketti Moret (Mona Maris), he investigates the fraudulent dealer's life. Judging that Ketti is truly evil, Henry prepares to murder her.
T.M.P. of The New York Times said, "What would you do if you only had six months to live? That is the problem which confronts Thomas Mitchell as an elderly professor suffering from an aortic aneurysm in Flight From Destiny. The same question has been pondered before on the screen, but seldom has it been dealt with so intelligently and entertainingly as in the new Warner drama at the Palace. Scenarist Barry Trivers has avoided artfully the pitfalls of a morbid theme by having Professor Todhunter regard his plight philosophically. And it was most fortunate that an actor of Mr. Mitchell's ability was selected to interpret the role, for he is a tower of strength."[2]