Spiezio spent five years with the Cardinals, being a member of the 1964 World Series and 1967 World Series championship teams, although he only played in the latter series. He also played in the 1968 World Series, which the Cardinals lost.
Notably, he also collected the first hit, first home run, and scored the first run in San Diego Padres history. This took place on April 8, 1969, in the bottom of the fifth inning against Houston Astros right-hander Don Wilson.[1]
In a nine-season career, Spiezio hit .238 (367-for-1544) with 39 home runs and 174 runs batted in, including 126 runs, 56 doubles, four triples, and 16 stolen bases in 554 games played.
Spiezio also played for four different minor-league teams in parts of five seasons spanning 1963–1972, posting a .263 average with 47 homers and 191 RBI in 383 games.
Ed Spiezio is the father of Scott Spiezio, who played in MLB from 1996 to 2007 and completed his major-league career with the Cardinals. They are regarded as the third father-son tandem in Cardinals' history.[citation needed]
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