In 2019, Marchese began writing The New York Times Magazine's Talk column, which featured long-form interviews with cultural figures and other notable people.[9]
In 2024, Talk transitioned into a weekly podcast and interview franchise, The Interview, hosted by Marchese and Lulu Garcia-Navarro.[10]
Media critics have praised Marchese for his ability to elicit unexpected, vulnerable, and profound answers from interview subjects.[11][12] He has said he spends up to six weeks preparing for an interview by reading everything available about an interviewee, including material not accessible via the Internet.[11] He comes to interviews with three to five pages of questions prepared in advance.[5]
In October 2024, Marchese claimed in an article that he wrote for the New York Times that as early as seven years old, he watched a film featuring Al Pacino and was able to appreciate that, "That's great acting."[13]
In November 2024, Marchese interviewed the doctor who euthanized his mother who was suffering from ALS.[14]
Marchese interviewed the influential anti-democracy blogger Curtis Yarvin for the Times in January 2025.[15]