DMTF1

DMTF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LLK
Identifiers
Aliases	DMTF1, DMP1, DMTF, MRUL, hDMP1, cyclin D binding myb like transcription factor 1
External IDs	OMIM: 608491; MGI: 1344415; HomoloGene: 8017; GeneCards: DMTF1; OMA:DMTF1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.12 Start 87,152,361 bp[1] End 87,196,337 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 A1 Start 9,168,801 bp[2] End 9,211,776 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of thyroid gland left lobe of thyroid gland right ovary left ovary right uterine tube body of uterus Achilles tendon right hemisphere of cerebellum canal of the cervix ventricular zone Top expressed in Rostral migratory stream genital tubercle tail of embryo saccule dermis cerebellar vermis human fetus lobe of cerebellum granulocyte spermatid More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific Cellular component nucleoplasm cytosol nucleus Biological process cell cycle regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II cell differentiation positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9988 23857 Ensembl ENSG00000135164 ENSMUSG00000042508 UniProt Q9Y222 Q8CE22 RefSeq (mRNA) NM_001142326 NM_001142327 NM_021145 NM_001110327 NM_011806 RefSeq (protein) NP_001135798 NP_001135799 NP_066968 NP_001103797 NP_035936 Location (UCSC) Chr 7: 87.15 – 87.2 Mb Chr 5: 9.17 – 9.21 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Cyclin-D-binding Myb-like transcription factor 1 is a protein that in humans is encoded by the DMTF1 gene.^[5][6]

References

1. GRCh38: Ensembl release 89: ENSG00000135164 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042508 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bodner SM, Naeve CW, Rakestraw KM, Jones BG, Valentine VA, Valentine MB, Luthardt FW, Willman CL, Raimondi SC, Downing JR, Roussel MF, Sherr CJ, Look AT (May 1999). "Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1)". Gene. 229 (1–2): 223–8. doi:10.1016/S0378-1119(98)00591-5. PMID 10095122.
6. "Entrez Gene: DMTF1 cyclin D binding myb-like transcription factor 1".

Further reading

• Försti A, Angelini S, Festa F, et al. (2004). "Single nucleotide polymorphisms in breast cancer". Oncol. Rep. 11 (4): 917–22. doi:10.3892/or.11.4.917. PMID 15010895.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Tschan MP, Fischer KM, Fung VS, et al. (2003). "Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns". J. Biol. Chem. 278 (44): 42750–60. doi:10.1074/jbc.M307067200. PMID 12917399.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• <Please add first missing authors to populate metadata.> (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Inoue K, Sherr CJ, Shapiro LH (1998). "Regulation of the CD13/aminopeptidase N gene by DMP1, a transcription factor antagonized by D-type cyclins". J. Biol. Chem. 273 (44): 29188–94. doi:10.1074/jbc.273.44.29188. PMID 9786929.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Hirai H, Sherr CJ (1996). "Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1". Mol. Cell. Biol. 16 (11): 6457–67. doi:10.1128/MCB.16.11.6457. PMC 231647. PMID 8887674.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.