The route, also known as Sheridan Boulevard, starts at US 285 in Denver and ends at US 36 in Westminster. There are interchanges with US 6, I-70, and I-76. In the area between I-70 and Colfax Avenue, the road lies just west of Sloan's Lake. State Highway 95 is generally considered to be the dividing line between Jefferson County on the west and Denver and Adams counties on the east.