He started his career with Lyon, going up all the way from the youth program to the B squad and ultimately in the club's top tier squad in the French Ligue 1, before moving to Tottenham Hotspur of the Premier League, and then back to Ligue 1 side Marseille before moving to his current club.
N'Jie made his senior international debut for Cameroon in 2014 and represented the nation at the Africa Cup of Nations in 2015, 2017, 2019 and 2021, winning the 2017 tournament and finishing third in the 2021 tournament.
On 15 August 2015, English side Tottenham Hotspur announced that the club had reached an agreement for the signing of N'Jie from Lyon, subject to international clearance and a work permit.[11][12] N'Jie agreed to a five-year contract with a reported transfer fee of €12 million (£8.3 million). N'Jie made his Spurs debut on 17 September in a Europa League group stage match against Qarabağ, coming on as a substitute for Andros Townsend. On 10 December 2015, he tore his medial collateral ligament (MCL) after a challenge by Jérémy Toulalan during a Europa League group stage match against Monaco. He had to undergo knee surgery for the MCL tear and was expected to out of action for at least 1–2 months, and possibly longer.[13] Working with injured teammate Jan Vertonghen during his recovery,[14] N'Jie eventually made his return on 8 May 2016 in a Premier League match against Southampton, in what would be his final appearance of the season.[15]
N'Jie made 8 appearances (all of them as a substitute) for Tottenham in the Premier League, his longest a 79-minute affair when he replaced the injured Nacer Chadli against Liverpool.[16] In addition, N'Jie made 5 appearances, starting in 2 of them, in Tottenham's Europa League campaign, and did not score a goal in all competitions.[citation needed]
Marseille
On 31 August 2016, N'Jie returned to Ligue 1, joining Marseille on a season-long loan deal.[17] Marseille had a €7 million option to buy him at the end of the loan, and Georges-Kévin Nkoudou headed to White Hart Lane on a permanent move in the opposite direction.[18] On 11 September, he made his debut as a substitute for William Vainqueur in the 68th minute away to Nice, and he scored his first goal two weeks later to equalise in a 2–1 home win against Nantes.[19]
On 16 July 2017, N'Jie made his move to Marseille permanent, signing for an undisclosed fee.[20] On 6 August, in the season opener against Dijon, he came on at half time for injured captain Dimitri Payet and scored two goals in a 3–0 win.[21] On 17 September, he scored both the goals in the away win over Amiens.[22] On 3 May 2018, he played in the Europa League semi-finals away to FC Red Bull Salzburg as Marseille played out a 2–1 away loss but a 3–2 aggregate win to secure a place in the 2018 UEFA Europa League Final.[23]
Dynamo Moscow
On 25 July 2019, N'Jie signed a four-year contract with Russian Premier League club Dynamo Moscow.[24] He scored his first goal for Dynamo on 27 October 2019, a late winner in a 1–0 victory over PFC CSKA Moscow.[25] N'Jie left Dynamo by mutual consent on 5 July 2022.[26]
Sivasspor
On 29 July 2022, N'Jie signed with Sivasspor on a two-year contract.[27]
N'Jie is a pacy forward[10][32][33] who likes to play on the shoulder of the last defender,[10] just off the front man.[34] He can also play off the wing,[9][32] and as dribbling is a key attribute of his game,[34] he likes to take on players when given the chance.[10] He frequently draws comparisons to Cameroon's all-time leading scorer and compatriot Samuel Eto'o,[10][32][34][35] with this comparison being asserted by Lyon chairman Jean-Michel Aulas.[33]
^"Clinton N'Jie est Olympien" [Clinton N'Jie is Olympien] (in French). Olympique de Marseille. 31 August 2016. Archived from the original on 2 September 2016. Retrieved 31 August 2016.