CP-226,269

CP-226,269
Identifiers
  • 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H19FN4
Molar mass310.376 g·mol−1
3D model (JSmol)
  • n4ccccc4N3CCN(CC3)Cc2cc1cc(F)ccc1[nH]2
  • InChI=1S/C18H19FN4/c19-15-4-5-17-14(11-15)12-16(21-17)13-22-7-9-23(10-8-22)18-3-1-2-6-20-18/h1-6,11-12,21H,7-10,13H2 checkY
  • Key:PQOIDBZLMJMYCD-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

CP-226,269 is a drug which acts as a dopamine agonist selective for the D4 subtype, which is used for researching the role of D4 receptors in the brain.[1][2]

References

  1. ^ Sharma A, Kramer ML, Wick PF, Liu D, Chari S, Shim S, Tan W, Ouellette D, Nagata M, DuRand CJ, Kotb M, Deth RC (May 1999). "D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia". Molecular Psychiatry. 4 (3): 235–46. doi:10.1038/sj.mp.4000522. PMID 10395213.
  2. ^ Basso AM, Gallagher KB, Bratcher NA, Brioni JD, Moreland RB, Hsieh GC, Drescher K, Fox GB, Decker MW, Rueter LE (July 2005). "Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test". Neuropsychopharmacology. 30 (7): 1257–68. doi:10.1038/sj.npp.1300677. PMID 15688083.
Stub icon

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.

Read other articles:

Historia de Barcelona

Puerto de Barcelona, grabado de Joseph Friedrich Leopold (c. 1720). La historia de Barcelona se extiende a lo largo de 4000 años, desde finales del Neolítico, con los primeros restos hallados en el territorio de la ciudad, hasta la actualidad. El sustrato de sus habitantes aúna a los pueblos iberos, romanos, judíos, visigodos, musulmanes y cristianos. Como capital de Cataluña y segunda ciudad en importancia de España, la Ciudad Condal ha forjado su relevancia con el tiempo, desde ser un...

 

Чарнолози

Село Чарнолозипол. Czarnołozy Координати 50°55′ пн. ш. 23°30′ сх. д. / 50.917° пн. ш. 23.500° сх. д. / 50.917; 23.500Координати: 50°55′ пн. ш. 23°30′ сх. д. / 50.917° пн. ш. 23.500° сх. д. / 50.917; 23.500 Країна ПольщаПольщаВоєводство Люблінське воє...

 

麗澤中学校・高等学校

この記事は検証可能な参考文献や出典が全く示されていないか、不十分です。出典を追加して記事の信頼性向上にご協力ください。（このテンプレートの使い方）出典検索?: 麗澤中学校・高等学校 – ニュース · 書籍 · スカラー · CiNii · J-STAGE · NDL · dlib.jp · ジャパンサーチ · TWL（2017年8月） 麗澤中学校・高等学校 北緯35度49分...

Загальні дебати 74-ї сесії Генеральної Асамблеї ООН

Загальні дебати 74-ї сесії Генеральної Асамблеї ООНТип Міжурядова організаціяПравовий статус АктивнаШтаб-квартира Штаб-квартира ООНРозташування Нью-ЙоркОфіційні мови Англійська, Арабська, Французька, Китайська, Російська, ІспанськаПопередник General Debate of the seventy-third...

 

Putri Pariwisata Sumatera Utara

Putri Pariwisata Sumatera UtaraLogo Putri Pariwisata IndonesiaPembuatJohnnie SugiartoNegara asal Sumatera Utara, IndonesiaRilisRilis asli2008 –SekarangPranala luarSitus web Putri Pariwisata Sumatera Utara merupakan kontes kecantikan berskala regional yang bertujuan memilih delegasi provinsi Sumatera Utara pada Putri Pariwisata Indonesia. Terhitung sejak keikutsertaan edisi 2008, Sumatera Utara belum pernah memenangkan Putri Pariwisata Indonesia. Prestasi tertinggi Putri Pariwisata...

 

Woippy

Woippy Woippy (Frankreich) Staat Frankreich Region Grand Est Département (Nr.) Moselle (57) Arrondissement Metz Kanton Le Sillon mosellan Gemeindeverband Metz Métropole Koordinaten 49° 9′ N, 6° 9′ O49.1511111111116.1513888888889Koordinaten: 49° 9′ N, 6° 9′ O Höhe 160–228 m Fläche 14,58 km² Einwohner 14.526 (1. Januar 2020) Bevölkerungsdichte 996 Einw./km² Postleitzahl 57140 INSEE-Code 57751 Website Woippy Kirche St. ...

Quân đội Đàng Trong thời Lê trung hưng

Võ sĩ Đàng Trong thế kỷ 17 trong tranh cuộn Trà ốc tân lục Giao Chỉ độ hàng đồ quyển 朱印船交趾渡航図巻 Quân đội Đàng Trong thời Lê trung hưng là tổng thể tổ chức quân sự của chúa Nguyễn bắt đầu từ khi Nguyễn Hoàng ly khai chính quyền Lê-Trịnh, cát cứ tại Thuận Quảng đến cuối thế kỷ 18. Vì sự chia cắt Đàng Ngoài – Đàng Trong, kể từ năm 1600, quân đội Đàng Trong dưới quy...

 

Great Egg Harbor River

River in southern New Jersey, United States 39°18′15″N 74°38′59″W / 39.30417°N 74.64972°W / 39.30417; -74.64972 Great Egg Harbor RiverShore of the Great Egg Harbor River between Penny Pot and Weymouth Furnace National Wild and Scenic RiverTypeScenic, RecreationalDesignatedOctober 27, 1992 The Great Egg Harbor River is a 55.0-mile-long (88.5 km) river in South Jersey.[1] It is one of the major rivers that traverse the largely pristine Pinelands,...

 

KLOU

Classic hits radio station in St. Louis For the airport known as KLOU, see Bowman Field (Kentucky). KLOUSt. Louis, MissouriBroadcast areaGreater St. LouisFrequency103.3 MHz (HD Radio)Branding103.3 KLOUProgrammingFormatClassic hitsSubchannelsHD2: Soft AC 103.3 HD2 The BreezeOwnershipOwneriHeartMedia(iHM Licenses, LLC)Sister stationsKATZ, KATZ-FM, KSD, KSLZ, KTLK-FM, W279AQHistoryFirst air dateFebruary 12, 1962 (1962-02-12) (as KMOX-FM)Former call signsKMOX-FM (1962–1982)KHTR (...

CorelDRAW Graphics Suite

CorelDRAW Graphics Suite 開発元 コーレル 最新版 2019 / 2019年3月12日 対応OS Microsoft Windows, MacOS種別 デザインツールの統合パッケージライセンス プロプライエタリ公式サイト コーレル株式会社テンプレートを表示 CorelDRAW Graphics Suite（コーレルドロー グラフィックス スイーツ）は、コーレル株式会社が発売している Microsoft Windows と MacOS 向けデザイン用アプリケーションソフト...

 

Sachia Vickery

American tennis player Sachia VickeryVickery at the 2023 Wimbledon ChampionshipsCountry (sports) United StatesResidenceHollywood, FloridaBorn (1995-05-11) May 11, 1995 (age 28)Miramar, FloridaHeight1.63 m (5 ft 4 in)Turned pro2011PlaysRight (two-handed backhand)CoachNabil BadekPrize moneyUS$ 1,817,321SinglesCareer record347–278 (55.5%)Career titles3 ITFHighest rankingNo. 73 (July 30, 2018)Current rankingNo. 168 (September 11, 2023)Grand...

 

Kalium klorat

Kalium klorat The structure of the ions in potassium chlorate The crystal structure of potassium chlorate Nama Nama lainKalium klorat(V), Potkrat Penanda Nomor CAS 3811-04-9 Y 3D model (JSmol) Interactive image ChemSpider 18512 Y ECHA InfoCard 100.021.173 Nomor EC 223-289-7 PubChem CID 6426889 RTECS number FO0350000 UNII H35KS68EE7 Y Nomor UN 1485 InChI InChI=1S/ClHO3.K/c2-1(3)4;/h(H,2,3,4);/q;+1/p-1 YKey: VKJKEPKFPUWCAS-UHFFFAOYSA-M Y InChI=1/ClHO3.K/c2-1(3)4;/h...

Guntur, India

Peta letak kota Guntur di negara bagian Andhra Pradesh Guntur, India adalah sebuah kota di negara bagian Andhra Pradesh di India. Kota ini terletak 64 km sebelah baratdaya Teluk Benggala. Kota Guntur terletak 1.600 km di sebelah selatan ibu kota New Delhi .Guntur adalah kota terbesar keempat di Andhra Pradesh. Kota ini memiliki perkiraan populasi 818.330 (514.707 per sensus 2001) dengan Aglomerasi Perkotaan sekitar 13.028.667. Kota ini juga merupakan pusat bisnis, industri pertanian...

 

Scooby-Doo! Camp Scare

2010 American filmScooby-Doo! Camp ScareDVD coverDirected byEthan SpauldingWritten byJed ElinoffScott ThomasBased onScooby-Dooby Joe Ruby and Ken SpearsProduced bySpike Brandt & Tony CervoneStarringFrank WelkerMatthew LillardMindy CohnGrey DeLisleScott MenvilleTara StrongLauren TomDee Bradley BakerPhil LaMarrStephen RootMark HamillMusic byRobert J. KralProductioncompaniesWarner PremiereWarner Bros. AnimationDistributed byWarner Home VideoRelease date September 14, 2010 (201...

 

Движение Сопротивления во время Второй мировой войны

Запрос «Движение Сопротивления» перенаправляется сюда; см. также другие значения. У этой статьи надо проверить нейтральность. На странице обсуждения должны быть подробности. В статье не хватает ссылок на источники (см. рекомендации по поиску). Информация должна быть п...

Markhor

Species of mammal For the village in Iran, see Markhor, Iran. Markhor Male markhor in captivity at the Augsburg Zoo Conservation status Near Threatened (IUCN 3.1)[2] CITES Appendix I (CITES)[2] Scientific classification Domain: Eukaryota Kingdom: Animalia Phylum: Chordata Class: Mammalia Order: Artiodactyla Family: Bovidae Subfamily: Caprinae Tribe: Caprini Genus: Capra Species: C. falconeri[1] Binomial name Capra falconeri[1](Wagner, 1839) Subsp...

 

Gastrolobium

Genus of plants endemic to Western Australia Gastrolobium Gastrolobium celsianum (Swan River pea) Scientific classification Kingdom: Plantae Clade: Tracheophytes Clade: Angiosperms Clade: Eudicots Clade: Rosids Order: Fabales Family: Fabaceae Subfamily: Faboideae Clade: Mirbelioids Genus: GastrolobiumR.Br. (1811) Type species Gastrolobium bilobumR.Br. Groups and species See text Synonyms[1] Brachysema R.Br. (1811) Cryptosema Meisn. (1848) Cupulanthus Hutch. (1964) Jansonia Kippist (18...

 

Joe Sewell

American baseball player (1898–1990) For the English footballer, see Joseph Sewell. For the US politician, see Joseph Sewall. For the American academic, see Joseph A. Sewall. Baseball player Joe SewellSewell, c. 1921Shortstop / Third basemanBorn: (1898-10-09)October 9, 1898Titus, Alabama, U.S.Died: March 6, 1990(1990-03-06) (aged 91)Mobile, Alabama, U.S.Batted: LeftThrew: RightMLB debutSeptember 10, 1920, for the Cleveland IndiansLast MLB appearanceSeptember 24,...

الليبرالية في اليابان

هذه المقالة يتيمة إذ تصل إليها مقالات أخرى قليلة جدًا. فضلًا، ساعد بإضافة وصلة إليها في مقالات متعلقة بها. (نوفمبر 2021) جزء من سلسلة مقالات حولالليبرالية التاريخ تاريخ الفكر الليبرالي مساهمات في النظرية الليبرالية تاريخ الليبرالية الكلاسيكية الأفكار ليبرالية سياسية ليبرا...

 

Law enforcement in Mexico

Overview of law enforcement in Mexico This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Law enforcement in Mexico – news · newspapers · books · scholar · JSTOR (February 2009) (Learn how and when to remove this template message) Ministerial Federal Police officers during a Federal Police Day ceremony in 2013La...

 

Strategi Solo vs Squad di Free Fire: Cara Menang Mudah!