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The men's 110 metres hurdles event at the 2007 Pan American Games was held on July 27–28.

Medalists

Gold	Silver	Bronze
Dayron Robles Cuba	David Payne United States	Yoel Hernández Cuba

Qualification: First 2 of each heat (Q) and the next 2 fastest (q) qualified for the final.

Wind:
Heat 1: +0.1 m/s, Heat 2: -0.2 m/s, Heat 3: +0.4 m/s

Rank	Heat	Name	Nationality	Time	Notes
1	1	Anselmo da Silva	Brazil	13.56	Q
2	1	Dayron Robles	Cuba	13.58	Q
3	1	Ryan Brathwaite	Barbados	13.61	q, PB
4	1	Bashir Ramzy	United States	13.61	q, PB
5	1	Dudley Dorival	Haiti	13.64	SB
6	2	David Payne	United States	13.77	Q
7	1	Jared MacLeod	Canada	13.78
8	2	Eric Keddo	Jamaica	13.79	Q
9	2	Enrique Llanos	Puerto Rico	13.89
10	3	Yoel Hernández	Cuba	13.91	Q
11	3	Hector Cotto	Puerto Rico	13.92	Q
12	2	Éder Antonio Souza	Brazil	13.93
13	3	Stephen Jones	Barbados	13.94	SB
14	3	Jorge McFarlane	Peru	14.18	PB
15	2	Mikel Thomas	Trinidad and Tobago	14.29
16	2	Francisco Castro	Chile	14.46
17	3	Ronald Bennett	Honduras	14.47
18	1	Christopher Bethel	Bahamas	14.90
	2	Shamar Sands	Bahamas	DQ
	3	Maurice Wignall	Jamaica	DNS

Wind: +0.4 m/s

Rank	Lane	Name	Nationality	Time
	6	Dayron Robles	Cuba	13.25
	5	David Payne	United States	13.43
	3	Yoel Hernández	Cuba	13.50
4	1	Ryan Brathwaite	Barbados	13.70
5	4	Anselmo da Silva	Brazil	13.72
6	2	Eric Keddo	Jamaica	13.91
7	8	Bashir Ramzy	United States	14.09
8	7	Hector Cotto	Puerto Rico	14.09