Many of his operas have explored people and events from African-American history. In a 1986 interview with writer Samuel R. Delany and historian Henry Louis Gates, Jr., Davis provides a detailed account of his influences and motivations for writing X, The Life and Times of Malcolm X.[9] In 1997 his opera Amistad, with a libretto by his cousin Thulani Davis, premiered at the Chicago Lyric Opera. Its ambition was recognized but the production received mixed reviews. It was accepted for production in 2008 at Spoleto Festival USA. It underwent a major revision and the production was highly praised. Opera Today said that the revised Amistad was "much leaner, more focused and dramatically far more effective than the original. And in so doing they [the Davises] created not only a masterpiece of American opera, but further a work that — against a contemporary horizon darkened by undercurrents of racism — resonates today far beyond Memminger and Spoleto USA."[10]
Davis has also explored Native American history in his work. His opera Wakonda's Dream (2007), with a libretto by Yusef Komunyakaa, is a tale of a contemporary Native AmericanPonca family in Nebraska and the history that affects them.[11]
His opera, Lilith, (libretto by Allan Havis) had its world premiere at the Conrad Prebys Music Center at UCSD on December 4, 2009. The story is about the demon figure of Jewish mythology who was sometimes said to be biblical Adam's first wife. It is set in a modern era.
He began working on the music for the opera The Central Park Five in 2014. An early version, titled Five, was performed in Newark, New Jersey in 2016 by the Trilogy Company.[3] The librettist for both the early and final versions was playwright Richard Wesley. The Central Park Five premiered on June 15, 2019, in a production by the Long Beach Opera Company in San Pedro, California.[12] In 2020 the work won him the Pulitzer Prize for Music.[5] He is the third UCSD professor in the university's 60-year history to win a Pulitzer.[13] He commented, "it's also very exciting for me that you can create political work that has an impact and speaks to issues in our society. I've done my career creating political works, and I never thought I would ever get a Pulitzer."[14] He learned that he had won the prize while in a Zoom meeting with music faculty colleagues, so they all heard the phone call; one of them later commented "Best Zoombomb ever!"[13]
Amistad (1997/revised 2008),[10] with libretto by Thulani Davis, about a case of an 1839 slave mutiny on a Spanish ship that reached the US Supreme Court, which ruled in favor of the Mende, freeing them[17]
Wakonda's Dream (2007), with libretto by Yusef Komunyakaa, about a contemporary Ponca family in Nebraska, and the spiritual journey of their son
Lilith (2009), with libretto by Allan Havis, explores a figure from Jewish mythology, sometimes said to be Adam's first wife, set in modern times
Lear on the 2nd Floor (2012), with libretto by Allan Havis, shifts the story of King Lear to feature a woman neuroscience researcher who has Alzheimer's disease, and her relationships with her three daughters and her late husband Mortimer, the Fool.