After a strong performance at the Tirreno–Adriatico, most notably finishing 3rd on the second stage and 2nd on the final stage (an individual time trial), he won his first professional race at the Tour of Flanders, one of cycling's five monuments. Following a successful solo attack on the second to last climb of the race, Oude Kwaremont, he managed to keep the gap to the chasing group which included several of the pre-race favorites, including previous winners Alexander Kristoff and Peter Sagan, for the remaining 17 km.[17]
2021–Present
In 2021, Bettiol won his first Grand Tour stage on day 18 of the Giro d'Italia in a solo fashion seventeen seconds ahead of the chase group.[18] In 2022, Bettiol took no victories but did place eighth in the road race at the UCI Road World Championships. He also won the combativity award for stage ten of the Tour de France, after attacking from the breakaway before being caught with nine kilometers remaining.[19]
The following season, he took a very early season win, capturing the 5.5 kilometer prologue of the Tour Down Under by eight seconds. In March 2024, he won Milano–Torino from a 30 kilometer solo ride, followed by taking fifth at Milan–San Remo three days later.[20][21]
