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The 1959 Calgary Stampeders finished in fourth place in the W.I.F.U. with an 8–8 record and failed to make the playoffs.

This was the Stamps last season at Mewata Stadium. They would move into their new home McMahon Stadium a year later.

Regular season

Game	Date	Opponent	Results		Venue	Attendance
Game	Date	Opponent	Score	Record	Venue	Attendance
1		Saskatchewan Roughriders	W 28–8	1–0
2		Winnipeg Blue Bombers	L 21–22	1–1
3		Winnipeg Blue Bombers	W 23–21	2–1
4		BC Lions	W 29–17	3–1
5		Saskatchewan Roughriders	W 28–10	4–1
6		Edmonton Eskimos	L 10–16	4–2
7		Edmonton Eskimos	L 20–27	4–3
8		BC Lions	L 8–14	4–4
9		Winnipeg Blue Bombers	L 10–15	4–5
10		BC Lions	L 10–28	4–6
11		Saskatchewan Roughriders	W 18–15	5–6
12		Winnipeg Blue Bombers	L 24–28	5–7
13		Saskatchewan Roughriders	W 43–13	6–7
14		Edmonton Eskimos	W 41–23	7–7
15		Edmonton Eskimos	W 25–24	8–7
16		BC Lions	L 8–10	8–8

^ "CFL.ca". Archived from the original on 2011-06-10. Retrieved 2009-08-09.
^ "Calgary Stampeders Historical Canadian Football League (CFL) Scores Since 1945". Archived from the original on 2009-03-12. Retrieved 2009-06-17.

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