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(2Z,6Z)-farnesyl diphosphate synthase

(2Z,6Z)-farnesyl diphosphate synthase
Identifiers
EC no.2.5.1.92
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

(2Z,6Z)-farnesyl diphosphate synthase (EC 2.5.1.92, cis,cis-farnesyl diphosphate synthase, Z,Z-FPP synthase, zFPS, Z,Z-farnesyl pyrophosphate synthase) is an enzyme with systematic name dimethylallyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 2 isopentenyl units).[1] This enzyme catalyses the following chemical reaction

dimethylallyl diphosphate + 2 isopentenyl diphosphate 2 diphosphate + (2Z,6Z)-farnesyl diphosphate

This enzyme was originally characterized from the wild hairy tomato Solanum habrochaites.

References

  1. ^ Sallaud C, Rontein D, Onillon S, Jabès F, Duffé P, Giacalone C, Thoraval S, Escoffier C, Herbette G, Leonhardt N, Causse M, Tissier A (January 2009). "A novel pathway for sesquiterpene biosynthesis from Z,Z-farnesyl pyrophosphate in the wild tomato Solanum habrochaites". The Plant Cell. 21 (1): 301–17. doi:10.1105/tpc.107.057885. PMC 2648096. PMID 19155349.

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