Transaminase

Transaminase merupakan enzim yang berfungsi dalam mengkatalisis perpindahan gugus amino.[1] Pada hati, salah satu jenis enzim ini berfungsi memindahkan gugus amino dari asam glutamat ke asam keto alfa[2] yang dapat digunakan oleh mayoritas asam amino. Selain itu, transaminase juga memiliki fungsi lainnya dalam mengkatalisis reaksi untuk memindahkan asam amino ke senyawa selain asam keto, yaitu ke aldehida untuk membentuk amina.[3] Vitamin B6 biasanya berfungsi sebagai kofaktor untuk enzim ini.[4]

Referensi

  1. ^ Jain, Buddhi Prakash; Goswami, Shyamal K.; Pandey, Shweta (2021). Jain, Buddhi Prakash; Goswami, Shyamal K.; Pandey, Shweta, ed. Chapter 9 - Clinical Biochemistry. Academic Press. hlm. 101–118. doi:10.1016/b978-0-12-822007-8.00001-5. ISBN 978-0-12-822007-8. 
  2. ^ M.Si, Dr La Ode Sumarlin (2023-02-14). BIOKIMIA: Dasar-Dasar Biomolekul dan Konsep Metabolisme. PT. RajaGrafindo Persada - Rajawali Pers. ISBN 978-623-231-171-8. 
  3. ^ "Transaminase". www.britannica.com (dalam bahasa Inggris). Diakses tanggal 24 October 2023. 
  4. ^ Manubolu, Manjunath; Goodla, Lavanya; Pathakoti, Kavitha; Malmlöf, Kjell (2018-01-01). Nunes, Carlos Simões; Kumar, Vikas, ed. Chapter 16 - Enzymes as direct decontaminating agents—mycotoxins. Academic Press. hlm. 313–330. doi:10.1016/b978-0-12-805419-2.00016-2. ISBN 978-0-12-805419-2. 

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