Laju filtrasi glomerulus

Diagram menunjukkan mekanisme fisiologis dasar dari ginjal

Laju filtrasi glomerulus (LFG) (bahasa Inggris: Gromerular filtration rate, disingkat GFR) adalah laju rata-rata penyaringan darah yang terjadi di glomerulus yaitu sekitar 25% dari total curah jantung per menit,± 1,300 ml . LFG digunakan sebagai salah satu indikator menilai fungsi ginjal. Biasanya digunakan untuk menghitung bersihan kreatinin yang selanjutnya dimasukkan kedalam formula.[1]

Komposisi dari hasil filtrasi glomerulus adalah kalsium, asam lemak, dan mineral. LFG di hitung dari hasil Koefisien filtrasi dan tekanan filtrasi bersih. Koefisien filtrasi adalah 12.5 ml/min/mmHg. Sedangkan Tekanan filtrasi bersih dapat dihitung dengan mencari selisih antara tekanan hidrostatik glomerulus dikurangi hasil penjumlahan tekanan onkotik glomerulus dengan tekanan kapsula bowman.[2]

Nilai normal LFG adalah 90 - 120 mL/min/1.73 m2.[3]

Referensi

  1. ^ (Inggris) Marcovitch, harvey (2005). black's meddical dictionary. A&C Black. ISBN 0-7136-6146-1. 
  2. ^ (Inggris) Guyton,Arthur (2006). physiology Guyton. elseviers saunders. 
  3. ^ (Inggris)[http://www.kidney.org/professionals/kdoqi/gfr_calculator.cfm},"kidney.org[pranala nonaktif permanen]". Diakses pada 18 Juli 2012.
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