ChEBI

ChEBI
Konten
DeskripsiDatabase kimia
Jenis dataChemical Entities of Biological Interest
Kontak
Pusat penelitianEuropean Molecular Biology Laboratory
LaboratoriumBritania Raya European Bioinformatics Institute
Kutipan utama[1]
Akses
Situs webChEBI
URL pengunduhanDownloads
URL layanan webWeb Service
Endpoint SparqlBIO2RDF
Perangkat
WebChEBI Website
Lain-lain
Frekuensi rilis databulanan
Kebijakan kurasiManually curated

ChEBI adalah singkatan dalam bahasa Inggris dari Chemical Entities of Biological Interest (Entiti kimia yang mempunyai kaitan menarik dengan biologi),[1][2] yaitu suatu database dan ontologi entiti molekuler yang berfokus pada senyawa kimia 'kecil', yang merupakan bagian dari upaya Open Biomedical Ontologies. Istilah "entiti molekuler" ("molecular entity") merujuk kepada apapun, yang berupa "atom, molekul, ion, pasangan ion, radikal, ion radikal, kompleks, konformer, dsb. yang berbeda secdara konstitutional atau isotopik, dapat diidentifikasi sebagai suatu entiti yang bisa dibedakan secara terpisah".[3] Entiti molekuler ini dapat merupakan produk alamiah ataupun produk sintetik yang memiliki potensi bioaktivitas. Molekul-molekul yang secara langsung dikodekan oleh genom, misalnya asam nukleat, protein dan peptida diturunkan dari pemotongan (cleavage) proteolitik, menurut aturannya tidak dimasukkan ke dalam ChEBI.

ChEBI menggunakan nomenklatur IUPAC, yaitu simbolisme dan terminologi yang dipakai oleh International Union of Pure and Applied Chemistry (IUPAC) dan Nomenclature Committee dari International Union of Biochemistry and Molecular Biology (NC-IUBMB).

Skop dan Akses

Semua data dalam database adalah non-proprietary atau diturunkan dari suatu sumber non-proprietary. Jadi dapat diakses dan tersedia secara bebas bagi semua orang. Lagipula, setiap item data dapat dilacak penuh dan secara eksplisit dirujuk ke sumber asalnya.

Data ChEBI tersedia melalui suatu "public web interface", Web Service dan download.

Lihat pula

Referensi

  1. ^ a b De Matos, P.; Alcantara, R.; Dekker, A.; Ennis, M.; Hastings, J.; Haug, K.; Spiteri, I.; Turner, S.; Steinbeck, C. (2009). "Chemical Entities of Biological Interest: An update". Nucleic Acids Research. 38 (Database issue): D249–54. doi:10.1093/nar/gkp886. PMC 2808869alt=Dapat diakses gratis. PMID 19854951. 
  2. ^ Degtyarenko, K.; De Matos, P.; Ennis, M.; Hastings, J.; Zbinden, M.; McNaught, A.; Alcantara, R.; Darsow, M.; et al. (2007). "ChEBI: A database and ontology for chemical entities of biological interest". Nucleic Acids Research. 36 (Database issue): D344–50. doi:10.1093/nar/gkm791. PMC 2238832alt=Dapat diakses gratis. PMID 17932057. 
  3. ^ IUPAC, Compendium of Chemical Terminology, edisi ke-2 ("Buku Emas") (1997). Versi koreksi daring:  (2006–) "molecular entity".

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